Marwood, there some researchers starting to support the Prana work.
Big Pharma know they have precious little at present except for a few ongoing large(too big to fail) trials which are 50/50 chance at best. When these big predators are embracing teamwork, you have got to think they have nothing.
http://www.alzforum.org/new/detail.asp?id=2648
A neutral group called Coalition Against Major Diseases (CAMD) is driving a large-scale effort at reforming the drug trial and drug approval process[to get their marginal drugs through?]
This CAMD meeting clearly illustrated that none of the stakeholders in AD drug development?individual pharma companies, academic trialists, a regulatory agency, or a patient group?can break the current logjam on their own.
Together, perhaps they can. This means data sharing.
Companies, perhaps humbled by their setbacks, are cooperating. Said a director at Pfizer, ?Continued investment in Alzheimer?s requires success, and success requires pre-competitive teamwork across organizations. CAMD provides the team framework.
The problem CAMD is addressing is intensifying. Since the approval of the current Alzheimer?s drugs in the 1990s and early 2000s, not a single drug program has succeeded, even though research has flourished. This includes most prominently a handful of anti-amyloid treatments, but also others, from Dimebon, valproate, DHA, statins, to rosiglitazone, NSAIDs, estrogen, vitamins E and B, homocysteine, and prevention with gingko biloba extract, for example. Not mentioned are countless lesser-known pharmaceutical compounds that died for various reasons without much public notice. In the last six years, Alzheimer?s disease has seen a 46 percent increase in mortality, where some other big diseases have had a modest decrease, said Cantillon. ?This reflects our absolute frustration of not coming up with better treatments,? he said.
The full article on the link is 4 pages.
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