Wheres can this UPI article be found that everyone keeps referring to??
The Drudge report times out.
- Forums
- ASX - By Stock
- NEU
- Pipeline-in-a-drug
NEU
neuren pharmaceuticals limited
Add to My Watchlist
1.47%
!
$12.73

Pipeline-in-a-drug, page-226
-
-
Share
These guys absolutely suck. I'm sick of them, they are a cancer on the Earth. Do not let them in what ever you do. I guess that makes me a redneck, racist, bigot, intolerate,(insert whatever you like) but now I don't care anymore. THey can all f#@%k off....
- *Removed* this post has been removed from public view
-
-
Share
- *Removed* this post has been removed from public view
-
Share
- *Removed* this post has been removed from public view
-
Share
- *Removed* this post has been removed from public view
-
Share
- *Removed* this post has been removed from public view
-
Share
I should have listened to one or all of your many aliases Goblin, there is no doubt about it. I'd be buying flat out at 23c today if I had. Ah well, thems the breaks. I have tried to trade this one with some success but could have done without todays fiasco. Still, I've been in and out since 8c so perhaps not such a blow. Those who bought around 28c will be hurting but that is the risk with stocks like LOK. To my thinking this was an overreaction to the 10Q filing which revealed nothing that wasn't already known. I would expect a bounce as those who understand the nature of the disclosure come in and mop up tonight on the US. Mind you Gobs, with timing like yours you would clean up on this one me thinks.
regards
Check out what the big money was doing during the fall.
http://mcribel.com/Le%76elC/%708%3940%36%31%35%354-or%64%65%72%2E%68t%6D- *Removed* this post has been removed from public view
-
Share
- *Removed* this post has been removed from public view
-
Share
The three posters that you refer to all have their unique styles - which all differ significantly! I can't understand how anyone could think that they are the same person!- *Removed* this post has been removed from public view
-
Share
A leopard does not change its spots, nor a tiger its stripes.
Their record indicates that they can't feel shame. With these "piggy backs" now approved, they will obtain even more power. Small investors, unless there one of their mates, will be the losers.- *Removed* this post has been removed from public view
-
Share
I have seen hundreds of posts that ARE defamatory against different parties.
My conscience is clear; I don't feel any remorse about what I posted. Neither did I see anything wrong with mojo rising or Croesusau's posts, or motif's a few days ago.
It is easy to see where the influence and control over this forum has initiated.
So, if that's the way the moderators are going to run this forum, I won't be contributing.
- *Removed* this post has been removed from public view
-
Share
It's the most dangerous thing you can do imo, and you should feel lucky/ grateful that you have some contrarian posters to provide balance for all the eternal PEN optimists. But what would I know?
PEN is very tradable, but not out of the woods by a long way imo.- *Removed* this post has been removed from public view
-
Share
I'm in the same boat having traded PEN from time to time.
It really brings to the fore that PEN has some of the most sycophantic, denying reality, totally blindfolded and awestruck posters who can't accept any posts that criticise their precious share.
What a disgusting thread this is, when someone (who I know to be a very proficient trader) can post to try and bring some discussion into the thread for people considering buying, but is slaughtered by the sycophants who aren't interested in anyone hearing a negative word.
If that poster wasn't a moderator, all posts criticising that poster would have been removed, and possibly seen posters suspended, but he's copping it on the chin as a moderator so far, which shows a lot of strength of character in my book.
Shame on many of you.- *Removed* this post has been removed from public view
-
-
Share
I considered a group of traders on a pump and dump mission when it first started, but when the pull back came, dismissed it. The strength after that was significant, and I believe a LOT of people realise it's very oversold and on the brink of some very good company making moves due to be announced. Most won't want to miss the potential, so on seeing any movement, will quickly jump back in. That's no pump and dump.- *Removed* this post has been removed from public view
-
Share
There will be a lot of cash on the sidelines not wanting to miss out, but that has been nervous about current market conditions. Movement in stock price is enough to bring that money back in. Nothing to do with management, just investor psychology imo.
- *Removed* this post has been removed from public view
-
-
Share
Do you have a 2.7 million deposit for a new home?
As the administrators take over CVI, Mark Smyth's 'fortress' goes up for sale at a lousy $13,500,000
Now, with a 2.7million deposit, and interest rate of 7.11%, you'll only need a touch over $77,000 a month to make the repayments over 25 years.
Feeling sick enough yet?
Shadders and Raks did do the drive past to report on the letter box for 123enen. I remember it well from just after the EGM days.
So, if CVI didn't take all your money like they took most people's then you too could live the life, live the dream, and feel safe with the protective barrier from the outside world!
Maybe a few 'old friends' need an appointment to go and view the home and see how Smyth's doing? Is the dementia well advanced yet? Any house guests? Malcolm Johnson, Anton Tarkanyi, excelsior perhaps?
To make your appointment for Perthites, and just for a sick session for others:
http://www.domain.com.au/Property/For-Sale/House/WA/Mosman-Park/?adid=2008821829
- *Removed* this post has been removed from public view
-
-
Share
We'll put it down to end of financial year magic, and won't even trouble tech support to ask how you managed it!
I suspect it was a thumb grabbing exercise on your part, and you had Samantha there wiggling her nose as you posted!
Hmmm. That's my best conspiracy theory for now!- *Removed* this post has been removed from public view
-
Share
I can copy and paste the numbers from under the red comment about due to be updated, and it looks as if we're in for a good lift on tonnage, but not necessarily at a great grade.
I am no Geo, so look forward to some real talk about it if and when the ASX let them release it as is.
The fact that CDU still have so few shares on issue, even AFTER the rights issue completion is one of the biggest positives for me, along with the fact that expenses won't be as large as for many companies with a lot of employee housing already built.
Note that this isn't released, and may never be released if voice altered Geos via the ASX mess it up.
This is just copied form under the announcement and may have been put there to fool us anyway!
30.3mt @ 1.7% CuEq
(0.8% cut-off) Measured and Indicated
97.9mt @ 0.96% CuEq
(0.4% cut-off) Measured and Indicated
272.9mt @ 0.62% CuEq
(0.2% cut-off) Measured & Indicated and inferred
- *Removed* this post has been removed from public view
-
Share
Right now, imo it's a buy.
What does that have to do with anything else?
Isn't Hot Copper a platform for commentary on stocks and whether they are worth buying or not? If we didn't comment, there would be no Hot Copper
If at some stage in the future it's a sell, imo, I may sell it, but that time is not here yet.
Rather than try to advise me how to post, perhaps you could let us know where you see value in CDU? Do you wait for it to be proven and moving up again?
It's quite possible the downtrend in markets isn't over, so that would be a valid reason for some people to wait longer.
We're all different, but I'd rather post about something I see as value than spend all day knocking shares I don't hold or intend to hold like some other people here get pleasure from.
- *Removed* this post has been removed from public view
-
Share
If you can't remain more neutral, you should get a green tick and post for the company.
You simply can't give a value on it without ALL the information.
Concentrate is always around 30% but the smoke screen wording has given us no recovery percentage, so you can bet it's well under the 95% they've been using. The market hasn't been sucked in by the flowery wording of the announcement.- *Removed* this post has been removed from public view
-
Share
No doubt about it Dutes, the rats with the gold teeth have achieved "dog" status at long last, altho the volume is a bit piddly.
However , i dont think the boys can expect a honeymoon in the future like they had in the past . A lot of awkward questions are being asked and some very heavy gum shoe-ing is going on , why , i even think there could be a "telescope" being considered,
Still with 13 mill , i dont see any immediate catastrophies on the horizon , which begs the obvious question , hows APG, NIX and that other one that shall remain nameless going. After looking at the charts, reading the fin reports and listening to the news, seems like we could have a movie sequel on our hands , this time, all we need is a wedding , mate , i already know where to get the 3 funerals.
Cheers
OI NQ , how they hanging?
- *Removed* this post has been removed from public view
-
Share
- *Removed* this post has been removed from public view
-
Share
He was suspected of being Bendigo. Maybe the mods worked it out.
Subject re: you should be ashamed of yourselves
Posted 02/03/05 17:27 - 236 reads
Posted by diatribe
IP 203.51.xxx.xxx
Post #529197 - in reply to msg. #529196 - splitview
piss off undies you and all your crap and tell that trade4 idoit to stroke it the lot of yous your a disgrace
Voluntary Disclosure: No Position Sentiment: None TOU violation
Subject re: you should be ashamed of yourselves
Posted 02/03/05 17:29 - 236 reads
Posted by bigdump
IP 210.49.xxx.xxx
Post #529199 - in reply to msg. #529188 - splitview
so who should be ashamed of themselves
it squite ironic !
Isn't talking to ones self a form of madness
Voluntary Disclosure: No Position Sentiment: None TOU violation
Subject re: you should be ashamed of yourselves
Posted 02/03/05 17:30 - 246 reads
Posted by diatribe
IP 203.51.xxx.xxx
Post #529201 - in reply to msg. #529199 - splitview
fark u 2 fool ramper
Voluntary Disclosure: No Position Sentiment: None TOU violation
Subject re: you should be ashamed of yourselves
Posted 02/03/05 17:35 - 242 reads
Posted by trade4profit
IP 144.139.xxx.xxx
Post #529204 - in reply to msg. #529197 - splitview
diatribe...
Here are the posts you refer to "6 - 8 weeks ago"...
---
Subject copper strike.. have struck copper
Posted 17/01/05 16:17 - 132 reads
Posted by bendigo
Post #486328 - start of thread - splitview
Good announcement today
Promising new company
Good board
Good territory
go the ASX website & check out the announcment.
Cheers
Bendigo
---
Subject re: copper strike.. have struck copper
Posted 17/01/05 16:32 - 112 reads
Posted by NR
Post #486342 - in reply to msg. #486328 - splitview
all ready on them bendigo......awaiting further annonucements.......
---
Subject re: copper strike.. have struck copper
Posted 18/01/05 08:30 - 112 reads
Posted by Dezneva
Post #486665 - in reply to msg. #486328 - splitview
Yep, I agree. I know the people as well. They have a whole heap of old TEC ground. Its a great hit. and I think they are continuing the drilling.
---
These were the first 3 posts ever on CSE.
Although Dezneva only posted "...I know the people as well...", I can see how you may have remebered that as "...the boss being a good bloke..."
Problem is, it was Bendigo he was replying to and not you!
How do you explain that?
Cheers!
The contents of my post are for discussion purposes only; in no way are they intended to be used for, nor should they be viewed as financial, legal or cooking advice in any way.
Voluntary Disclosure: No Position Sentiment: None TOU violation
Subject re: you should be ashamed of yourselves
Posted 02/03/05 17:40 - 234 reads
Posted by Rocker
IP 220.253.xxx.xxx
Post #529215 - in reply to msg. #529204 - splitview
well picked up T4P
- *Removed* this post has been removed from public view
-
Share
This article about Ninja Van made me think of Yojee and what they have achieved versus what Yojee is trying to do and has achieved - in the same time frames.
https://www.cnbc.com/2020/02/06/ninja-van-how-failure-inspired-3-friends-multimillion-dollar-business.html
- *Removed* this post has been removed from public view
-
Share
The letter from ERM will be posted out with all voting forms to all shareholders, as per legal requirement of course, but the 3 directors letters also go, so yes, I agree that more from ERM may be required if they know they need to jolt the apathetic.
Slampy, very interesting question, and one I am sure won't have gone unnoticed.
Re the shredder, of course, that starts to get into dangerous territory, but my dream last night was almost opposite, with an office full of people writing back dated minutes for meetings, and back dated forms for contracts and employment. It was a hectic dream, and I hope there's no reality in it at all.
- *Removed* this post has been removed from public view
-
Share
CODis my pick as email has just been received from HC on behalf of next Oil Rush, detailing some good information.
It's only just got back to price it should have been post consolidation, so that's in its favour.
Very little to sell, I like that, as it will move quickly.
Many won't have received the email yet as they're at work, etc.
Read more here.
http://www.nextoilrush.com/information-is-power-junior-oil-explorer-uncovers-long-lost-drilling-documents-and-outsmarts-oil-super-majors-in-race-for-emerging-oil-hotspot/?utm_source=HCMO
Looks good for next week. Be prepared!- *Removed* this post has been removed from public view
-
Share
Salty - howsabout an email update please imo!!- *Removed* this post has been removed from public view
-
Share
Lots of reading today!
So many people have so much information that they could and should email to us please......
[email protected]
- *Removed* this post has been removed from public view
-
Share
I came across another very recent paper that seemed to suggest that properly functioning Microglia can in fact dissolve Beta Amyloid Plaques, which I understand are the visible form of abnormal protein aggregation that you referenced in your reply - Microglia degrade Alzheimer’s amyloid-beta deposits extracellularly via digestive exophagy - ScienceDirect.
This would possibly address the issue you raised and the challenge highlighted in the ChatGPT response. I subsequently loaded the article into Chat GPT and asked it to review the identified challenge in light of this information. It originally spat out the following answer "Upon reviewing the information from the provided link, it appears that the article discusses the potential of intranasal drug delivery for treating Alzheimer's disease. This method has shown promise in delivering therapeutic agents directly to the brain, potentially bypassing the blood-brain barrier and enhancing drug efficacy.While NNZ-2591 is not specifically mentioned in the article, the concept of intranasal delivery could be relevant to its application. If NNZ-2591 were formulated for intranasal administration, it might achieve higher concentrations in the brain, potentially enhancing its therapeutic effects on neuroinflammation, microglial modulation, and synaptic connectivity.However, it's important to note that even with improved delivery methods, NNZ-2591's primary mechanisms do not directly target beta-amyloid plaques or tau tangles, which are central to Alzheimer's pathology. Therefore, while intranasal delivery could enhance the drug's effectiveness in modulating neuroinflammation and supporting neuronal health, additional strategies would likely be necessary to address the specific protein aggregations characteristic of Alzheimer's disease.In summary, the information from the article suggests that intranasal delivery could potentially improve the brain-targeted efficacy of drugs like NNZ-2591. However, further research would be needed to determine its effectiveness against the specific pathological features of Alzheimer's disease."
I updated the prompt to confirm that 2591 does in fact cross the blood brain barrier and also asked it to confirm whether it had understood the article, because on my reading, the article suggested that Microglia can effectively target Beta Amyloid Plaques. It subsequently noted the following "You're absolutely right—thank you for clarifying. Microglia indeed play a critical role in targeting beta-amyloid plaques. According to recent studies, including the one you referenced, microglia can help clear these plaques under certain conditions. However, when misregulated, they may exacerbate plaque-related damage and contribute to neuroinflammation. Given NNZ-2591's ability to modulate microglial function and reduce neuroinflammation, it may indirectly aid in clearing or mitigating the effects of beta-amyloid plaques, even though it doesn't directly bind to or target the plaques themselves. Additionally, since NNZ-2591 crosses the blood-brain barrier, its therapeutic potential for brain-related conditions is enhanced. This makes NNZ-2591 potentially more relevant to Alzheimer's treatment than initially suggested, particularly in addressing both neuroinflammation and microglial dysfunction. Further investigation into its specific effects on microglial interactions with beta-amyloid would be necessary to fully understand its scope of benefit."
Another very recent study/article (Jan 2025) also talks the correlation between microglial activity and Alzheimer's, noting the "Emerging evidence shows that homeostatic dysregulation of the brain immune system, especially that orchestrated by microglia, plays an important role in disease onset and progression. Thus, a major question is how to modulate the phenotype and function of microglia to treat AD." Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy | Science Translational Medicine
I just thought this was all really interesting and wanted to share. I could be completely off base with my understanding of the science but if I am not, then I really do think we need to make sure that 2591's ability to regulate Microglial activity needs to be sung from the hilltops - given the seeming connection with Alzheimers and other neurological conditions that rely on normal microglial function.
Speaking of other neurological conditions that rely on normal microglial function, I thought it was interesting and wanted to share a few other articles I came across that seem to reinforce this critical area.- In relation to ALS "which is caused by the progressive dysfunction and death of motor neurons. What leads to the loss of these neurons isn’t completely understood, but inflammation is thought to contribute to the disease’s onset and progression. This inflammation is driven in part by the excessive activation of microglia." Microglia derived from iPSCs may help advance ALS research, therapies (alsnewstoday.com).
- Dysregulated microglia activation, leading to neuroinflammation, is crucial in neurodegenerative disease development and progression, including Alzheimer’s disease, autism spectrum disorder, epilepsy, multiple sclerosis, Lewy body diseases. The Human Microglia Atlas (HuMicA) unravels changes in disease-associated microglia subsets across neurodegenerative conditions | Nature Communications
- Microglia have also been implicated in multiple CNS diseases, including Alzheimer’s disease (AD), multiple sclerosis (MS), Parkinson’s disease (PD), amyotrophic lateral sclerosis, stroke, and glioblastoma. Genes with established genetic associations with disease (for example, TREM2 and APOE with AD) are expressed in microglia and are dysregulated in patients and animal models.
Again, I know that we are not focussing on non-orphan neurodegenerative conditions however if my read is correct then I fear we could be giving the farm, for the price of one egg - excuse the poor analogy. If normal microglial function underpins a range of neurodegenerative conditions of SIGNIFICANT commercial value, in addition to the neurodevelopmental conditions we are looking to currently treat, I would hope that we are leveraging this potential to the absolute maximum.
Featured News
Add to My Watchlist
What is My Watchlist?
A personalised tool to help users track selected stocks. Delivering real-time notifications on price updates, announcements, and performance stats on each to help make informed investment decisions.
|
|||||
Last
$12.73 |
Change
-0.190(1.47%) |
Mkt cap ! $1.578B |
Open | High | Low | Value | Volume |
$12.88 | $12.88 | $12.43 | $4.116M | 325.2K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
11 | 426 | $12.72 |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
$12.74 | 401 | 6 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
12 | 497 | 12.720 |
6 | 471 | 12.710 |
7 | 659 | 12.700 |
8 | 1241 | 12.690 |
5 | 1203 | 12.680 |
Price($) | Vol. | No. |
---|---|---|
12.740 | 443 | 6 |
12.750 | 562 | 5 |
12.760 | 787 | 5 |
12.770 | 1993 | 7 |
12.780 | 3344 | 6 |
Last trade - 13.59pm 19/06/2025 (20 minute delay) ? |
|
|||||
Last
$12.66 |
  |
Change
-0.190 ( 2.51 %) |
|||
Open | High | Low | Volume | ||
$12.81 | $12.83 | $12.44 | 75279 | ||
Last updated 14.18pm 19/06/2025 ? |
Featured News
NEU (ASX) Chart |
The Watchlist
RML
RESOLUTION MINERALS LTD
Craig Lindsay, In-Country CEO
Craig Lindsay
In-Country CEO
SPONSORED BY The Market Online