AlCp, I want to thank you for your strong consistent commentary in light of the verbal battles you have with those who consistently state the opposite view. I understand what they say, and how they feel, and I even agree with some of their statements, but their constant negativity saying the same group of negative comments over and over and over and over again, makes me wonder if they now suffer from depression.
This is what keeps my focus, after the disappointment of Hervax, Vax, and PD1 vax being deprioritised.
In Jan 24 they reported their ph1 CF33 mono and combo Vaxinia dose escalation from low to mid dose results.
38 ppl total - 14 IT & 19 IV evaluated.
In the 14IT - 7 lesions shrunk with 3 'completely eradicated'.
In the 17IV - 9 achieved SD
Something's obviously working.
So they picked their best bet target for a ph1, because of good result in an unmet need and recieve Fast Track and orphan status. Nice.
This next Vaxinia data drop will be from a year of mid dose to obd data on the same cancer from 10-20 patients that gave us 2 of the 3 CRs in low to mid dose. At a minimum the potential for that ratio of good results is still there, irrespective of what the SP is doing.
All I'm waiting on is this data, because the SP is a disappointing lost cause atm. Im hoping if the data is great, it will run. If the data is average the manipulators may allow a pump and dump, if its disappointing IMU will be gone.
More than anything I hope and pray that its successful for all cancer sufferers it could help.
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