Ann: Ryoncil Commercial Launch Update and Product Pipeline, page-218

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Kerebrad

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03/02/25

07:16

Post #: 77672486
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Originally posted by LeftYahoo: ↑

This is straight from the PR:

"SURVIVAL in adults with SR-aGVHD who have failed at least one additional agent, such as ruxolitinib,
remains as low as 20-30% by 100 days.1,2 In contrast, 100-day SURVIVAL was 73% after Ryoncil®"

So, survival vs survival. A direct comparison of rux vs rem-l efficacy would require an RCT that has never been done. I don’t believe the company is trying to make such a comparison. Rather, they've ceded the secondary therapy slot to ruxilitinib, at least for the time being.

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Following its approval …

As a patient, as a doctor, as family, given a choice between Rux and Ryoncil ??? FDA need to be given the fastest route possible to allow the obvious.

One would also think, given up-to-date results

Same with Heart x 2
Same with Back
Same with IB Crohns etc
Same with ARDS

I think I’m turning into Molly !!!

MSB Price at posting: $3.17 Sentiment: Hold Disclosure: Held
9 Upvote

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