watch ymyc tonight wed 14/3, page-10

"Clearly CVac isn't being tested in that way yet, but there has been commentary about trialling it pre chemo. (DNDN are exploring the same)"

This is the holy grail IMO, and could see stunning results. Needless to say there is a certain resistance from some quarters to see this happen.
I have raised this issue with Martin Dr Frazer, Dr Frazer's response to my questions below:

- Have you done any testing pre chemotherapy? No

- If not, do you plan on conducting these trials in the future? After we obtain approval, we may broaden out the times of administration in additional clinical studies.

- What would be the proccess required to gain FDA approval, ie full PH I, II AND III? It's a difficult question. We'd probably need to start with concomitant administration with chemotherapy and work back from there.

- Will the current Ph III testing only allow you to administer CVac post chemotherapy?For EU, US and Australia-Yes