Ahjay, I'll answer your question with a link to Wikipedia
http://en.m.wikipedia.org/wiki/Data_monitoring_committee
Basically, all data and progress is overseen by an independent committee. Once the endpoint is reached, then people at prima are informed.
Stoody, yes, they would know the stats of pfs and OS, and coil therefore make inferences on progress, but they don't know if it is th Cvac group or the control that is doing well. They have to prove a difference between Cvac and control, and they won't know what is going on.
Hangas....safety has already been shown and proven. They are now testing efficacy
wakey wakey mr market, page-101
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