PYC pyc therapeutics limited

slamming on the rnai brakes

  1. 315 Posts.
    The latest Novartis action to shutdown RNAi research based on:

    "... the lingering problems associated with delivering these therapies tied to the small number of relevant targets they could shoot for drove the move."

    http://www.fiercebiotech.com/story/breaking-novartis-slams-brakes-rnai-development-efforts/2014-04-14

    This contrasts with the EET and potential Phenomica progress in which:

    - The delivery problem has been completely resolved;

    - The targeting problem looks like it can be feasibly addressed; and

    - The complex RNA payload against gene expression can be replaced with a simple payload against phenotype expression.

    Compare the multiple billion$ directed to RNAi programmes - where Phylogica's tens of million$ actually has produced a significantly more effective platform.
 
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