dosing commenced, page-31

"Initial patient cohorts will be treated
with a sub therapeutic dose of TT-034
to ensure that there are no unexpected safety
concerns, before proceeding to higher, potentially therapeutic doses."

my understanding is that the first dose is to test for safety and is not aimed for reducing the viral load ... so we should not be expecting a reduced viral load in the first dose ... if that happens then fantastic but should not be expected until the higher therapeutic doses are given

therefore if the first dose only establishes safety it is a good outcome