Method of Determining, Identifying or Isolating Cell-Penetrating Peptides, this was originally filed on May 23, 2011 and then the Published date is 22 May, 2014.
I can't seem to find any reference to the initial date May 23, 2011 in company announcements. I thought the company would need to inform the market of any patent filings? If anyone can offer any help, would be much appreciated.
The present invention provides a method of determining or identifying or isolating a cell-penetrating peptide (CPP) or analog or derivative thereof having cell-type selectivity and/or at least capable of passing through a Blood Brain Barrier of an animal subject. This invention also provides CPPs and analogs and derivatives thereof, such as those set forth in SEQ ID NOs: 1-27 of the Sequence Listing, and compositions comprising one or more of the CPPs, including conjugates in which a CPP or analog or derivative thereof is linked to a cargo molecule. The invention also provides methods for transporting cargo molecules across cell membranes to specific locations within cells, and for treating, preventing and/or diagnosing diseases that are treatable by a cargo molecule to which a CPP or analog or derivative of the invention is attached. The invention also provides tailored peptide libraries for use in identifying or isolating CPPs.
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