Thanks tmenadue
A few things that jumped out at me
1st presentation Professor Venge
Rapid rule in is LIFE SAVING
Rapid rule out is Money $aving
Are all POC Troponin tests the same sensitivity? nope
'We cannot distinguish a short term change'
Current POC assays 'obviously' inferior, would have missed out on 30%-50% of predictions of death due to myocardial infarction.
Current POC assays leave doubt in the mind of the decision maker, they doubt them so much they send another sample to the lab, which decreases the utility of the POC device (why bother)
Further sensitivity is needed
Sounds like "oils aint oils"
2nd Presentation - Professor Bingisser
43% of presentations to an emergency department are non-urgent! They are being swamped!
Emergency medicine = immediate reward junkies!
Prone to make mistakes from quick decisions, adherence to a standard protocol reduces mortality (death)
Acute coronary syndrome - Is it unstable angina or or STEMI/NSTEMI????
Troponin testing = rule in or rule out (High sensitive POC = rule in/out at the door)
Current LAB turn around 'vein to brain' = 2 hours
Current POC 'vein to brain' = 15 mins but is it accurate???
If they follow a 3 hour retest protocol
3hour and 20 mins POC not 5 hours LAB - but it is not accurate!
WHAT WE NEED IS POC TEST WITH HIGH SENSITIVITY! THE CURRENT ONES DON'T CUT IT
Presentation 3 - Joreon Nieuwenhuis - (The solution!)
Many advantages of multiplexing such as more accurate reading with, extended dynamic range (up to 4-5 orders of magnitude WOW); controls built in = reliable and trusted!, higher and lower concentrations for averages, detection of different proteins etc etc WOW
Measures to ensure NOTHING CAN GO WRONG - No calibration needed WOW
It is a reliable outcome.
Results connectivity via the cloud to the patient bedside, nurse or doctors ?IPhone, into the consumers electronic record and billing. Also maintenance via the cloud! WOW
Field trials NOW
Robust cost effective cartridge
First production line up and running, second line being developed.
DOES THE PERFORMANCE MEET THE CLINICAL DECISION MAKING NEEDS? YES
Very comparable correlation even down to the lower concentration level, when comparing Mincare to lab!!!!!
"It is exactly this gap that we try to close with the minicare technology"
Final fine tuning of the assay and soon we will start working towards the clinical trials.
No need to send samples to the lab, as the POC test is comparable. DISRUPTIVE TECHNOLOGY
The guy asking the question didn't get it, why buy a new lab and put it in the A&E that will take a 24 manned station and still 40 minutes turn around.............. High co$t for no benefit, just get a minicare device!
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Given that the protocol looks for a 3 hour window to 'rule in or rule out', what if the clock could start ticking at the GP office or ambulance arrival at the home................. WOW
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