New Philips Minicare study, page-2

Innovation in biosensor nanotechnology

The use of magnetic nano particles enables the Magnotech technology to measure minute concentrations of target molecules: at a sensitivity more than 500 million times of a glucose test

	Magnotech – the science behind it

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The Magnotech technology is based on the use of magnetic nano particles to concentrate, separate and detect target molecules. This new type of biosensor technology enables blood testing in a more patient friendly way providing results in a matter of minutes at the point-of-care. All assay reagents are contained in the disposable cartridge. Once a droplet of sample is applied to the cartridge the sample is automatically drawn in by capillary forces. After the measurement chambers have been filled, no other liquid movement takes place. The entire assay process within the cartridge is executed by controlled movement of the magnetic nano particles within the cartridge using external magnetic fields. After a short incubation stage the amount of bound nano particles, proportional to the concentration of the detected biomarker in the sample, is detected optically.

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Philips Magnotech technology platform features: Active magnetic assay control enables a precision typically associated with large laboratory analyzers, Concentrating the magnetic particles near the sensor surface accelerates the binding kinetics resulting in a high sensitivity, Efficient sample utilization allows working with small sample volumes; a measurement can be performed with a single sample droplet, Supporting multiple measurement chambers per cartridge allows detection of several target molecules in a single measurement, Use of dry reagents enables a cost-effective cartridge to be made with good stability properties.

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