ASCO Poster

  1. 47 Posts.
    The ASCO poster is now available on the company website. I'm no expert but there doesn't seem to be much that we didn't already know.

    Below is an extract from the 'Future Directions' section of the poster. Ipililumab is one of the drugs making it to all the news stories right now, so it's pleasing that we are already underway with a joint trial. Nost sure if that info was already out there or not.

    Future Directions

    The observation of CVA21-induced immune cell infiltration in injected melanoma lesions suggests that combination of this treatment with checkpoint inhibitors such as anti-CTLA-4 and/ or anti-PD-1 might result in enhanced antitumor activity, as was shown in preclinical murine models

    • Clinical evaluation of the activity of intralesional injection of CVA21 in combination with systemic administration of ipilimumab in patients with unresectable melanoma is currently underway

    • Further evaluations of both intralesional and intravenous administration of CVA21 in combination with additional immune checkpoint inhibitors are in planning
 
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