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Mix and Go research, page-9

  1. 2,515 Posts.
    Hi Biotech
    This is from the Oakridge AACC 2013

    It appears that the plus =+ in mix+Go was a mistake by me.
    The & appears in the report below.
    So the Trademark IS Mix&Go

    As the products listed in the post earlier are called Mix&Go .And as Mix&Go is an Anteo Trademark then surely it must follow that there is Mix&go in the products




    Analysis of multiplex assays using a common bead and slide surface. Jennins D, Chung E, Cooper SJ, Fontanelle BT, Gao Y, Koudijs MM, Yang L, Ling T, Vukovic P, Wong A, Maeji NJ. Anteo Diagnostics Ltd., Brisbane, Australia. To simplify protein binding for immunoassays and bioseparations, metal polymer solutions call Mix&GoTM were developed. These aqueous polymer solutions bind to any surfaces having electrondonating potential to form an activated surface within minutes. In turn, this activated surface will bind proteins in minutes, or this activated surface can be stored for years with no loss of protein binding activity. Mix&Go represents a “one-size-fits-all” surface chemistry approach in situations where maximum protein performance and uniformity at the surface interface is of importance. Mix&Go can activate particles such as iron oxide nanoparticles (IONPs), gold colloids, latex, and many other particles while minimizing their tendency for aggregation. As well, Mix&Go can activate planar surfaces such as bare silica, ceramics and polystyrene surfaces commonly used in array applications. Regardless of the underlying material or whether the format is a particle, film, or slides, Mix&Go creates a common chelating surface for protein binding. To determine whether antibodies bound to Mix&Go surfaces behave the same regardless of the underlying material, multiplex assays were tested on both Mix&Go activated Luminex beads and glass slides. Each exemplifies the two most common approaches to multiplexing but with one, the underlying surface is latex polymers with antibody coupled beads stored in solution. The other is glass, a material that usually needs to be well-coated to protect protein stability, and antibodies are stored dried on the surface. There are other differences between the two formats so with a common set of capture antibodies, the influence of these differences were investigated to determine whether the patterns of outcomes of a multiplex assay were affected by the underlying material. Since it is well known that the performance of antibodies are affected by the mode of binding, this multiplexed data from Mix&Go beads and glass surfaces were compared to conventional amide (Luminex beads) and epoxy (glass slides) chemistries.
 
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