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Host response: A trigger for neurodegeneration?

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    Dr. Tanzi is heavily cited in this article.

    Nature Microbiology
    News and Views
    Host response: A trigger for neurodegeneration?

    Roman M. Stilling & John F. Cryan

    A new study provides clues to the physiological function of amyloid-β (Aβ), the plaque-forming peptide associated with Alzheimer's disease and finds a role for Aβ in fighting infection in the brain, by entangling pathogens in a web of amyloid fibrils. These data add to a growing appreciation of the role of microorganisms in neurodegenerative disease.
 
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