I'd take the particular claims - "Some of them even had their voices come back" - with a huge dose of salt. But your wider point is valid: positive word of mouth is likely driving a surge in enrollment.
It seems to me that the trial has morphed. Initially it was about safety and side effects, with efficacy necessarily a secondary concern in a phase 2 trial. But the additional enrollments are all at the highest dose (or placebo). That suggests safety is no longer a significant concern. The trial is double-blind, but safety and toxicity would be monitored throughout by a separate committee. This committee must have given the green light for maximum-dose v placebo for all new enrollments. And that suggest the objective of the extension is really about efficacy, to give the best possible chance to record a statistically significant difference between drug and placebo.
This is important. I'd imagine there would be a significant placebo effect in a trial like this; the parents invest so much hope in a trial like this. So congratulations to the company for being agile and flexible enough to extend the trial in such a way that gives it the best chance of demonstrating efficacy.
Doesn't mean the drug works, but they're giving it the best chance to demonstrate if it does or not.
GLTAH
- Forums
- ASX - By Stock
- NEU
- Story about Trof trial
Story about Trof trial, page-4
-
- There are more pages in this discussion • 16 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
Add NEU (ASX) to my watchlist
(20min delay)
|
|||||
Last
$13.61 |
Change
0.280(2.10%) |
Mkt cap ! $1.739B |
Open | High | Low | Value | Volume |
$13.49 | $13.64 | $13.30 | $4.821M | 356.4K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
3 | 3602 | $13.55 |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
$13.66 | 1655 | 2 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
3 | 3602 | 13.550 |
1 | 4057 | 13.540 |
1 | 1947 | 13.530 |
1 | 1676 | 13.520 |
1 | 1947 | 13.510 |
Price($) | Vol. | No. |
---|---|---|
13.660 | 1655 | 2 |
13.690 | 1947 | 1 |
13.700 | 1000 | 1 |
13.720 | 1947 | 1 |
13.740 | 1947 | 1 |
Last trade - 16.10pm 12/09/2024 (20 minute delay) ? |
Featured News
NEU (ASX) Chart |