No, what would put the fear of God into Merck or BMS would be one of their competitors exclusively snaffling up a combination partner that makes the combination unbeatable. The bigger the indication the more fear. E.g. lung cancer since the market is HUGE.
The poker game is how long they can wait to prove that any given combination is the best for a given indication, or even one of the top few. More confidence equals more money that will be put on the table. Big stakes. I hope Malcolm is a good poker player.
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