SRX 0.00% 19.0¢ sierra rutile holdings limited

Sirt result, page-77

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    Maybe another contributor to the relatively poor tumor response rate (apart from prior TACE) was the dose given.

    Recommended doses I found from Dezarn et al 2011 for Y90

    Est degree of liver involvement
    >50% 3000 MBq
    25-50 2500 MBq
    <25% 2000 MBq

    By comparison page 20 gives delivered doses of just 1394.5 MBq in the study

    There may be reasons for the lower doses, such as shunting of blood flow to other organs, or problems caused by prior treatment with TACE, but surely the lower dose will be less effective.
 
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