IMU Spotlight on Company and Management

Guys think its time to start an informational thread for existing and new holder and people wanting to understand more about their investment - after all there is a thread for charts - a place to come to understand whats happing at IMU and what to expect so ill start with their website and board of directors so we can all understand  WHO IS running OUR  company and how much industry clout they have and what stage they are up to - including product coverage - cheers G101


http://www.imugene.com/
^{Imugene is an immuno-oncology focused biopharmaceutical company developing HER-2+ gastric and breast cancer immunotherapies.  Our mission is to build a pipeline of B-cell peptide cancer vaccines}

Our lead product is HER-Vaxx, a proprietary therapeutic cancer immunotherapy that stimulates a polyclonal antibody response to HER-2/neu, the same biomarker targeted by the $US6.9 billion per annum drug Herceptin®.
Click here to view latest Imugene Fact Sheet
Click here to view video that introduces HER-Vaxx and explains how it works
Click here to view Imugene's current share price
Click here to view Leslie Chong interview with Medicalresearch.com "Imugene Building Pipeline of B Cell Peptide Cancer Vaccines".
Click here to read "What's Hot & What's Not in Immuno-Oncology Licensing.  Dr Axel Hoos is interviewed as part of an expert panel.

HER-Vaxx has successfully completed a Phase 1 study in breast cancer and has commenced in 2017 a Phase 1b/2 study in  HER2+ gastric cancer.  Gastric or stomach cancer is the second most common cause of cancer-related death in the world and the fourth most commonly diagnosed cancer, with over 1,000,000 new cases diagnosed each year.
HER-Vaxx has shown success in stimulating the production of lifesaving HER-2 antibodies in early-stage cancer patients enrolled in the initial clinical trial. Its further development is directed towards providing a natural, potentially more potent alternative to Roche’s popular injectable antibody, Herceptin®, which have become one of the world’s bestselling cancer drugs with annual sales in excess of $US6.7 billion (Roche Investor Update 30/1/17).
Imugene in partnership with the Medical University of Vienna is working to discover and develop mimotope-based immunotherapies against validated and new oncology targets.

This partnership has the potential to create game-changing B Cell peptide vaccines that would replace or augment conventional monoclonal antibody therapies.
Imugene is also building a pipeline of small molecule immuno-oncology drugs.   Arginine is a critical amino acid for the health of cancer fighting T-cells and depletion of it limits the effectiveness of T-cells to fight tumours.  We are leveraging our core expertise in tumor biology and medicinal chemistry to develop small molecule selective arginine modulators.
Imugene’s corporate headquarters are located in Melbourne, Australia with most of the scientific team in Vienna, Austria.
Latest News

18/02/2018
Imugene arginine modulator demonstrates activity in melanoma cancer model
11/02/2018
Novel Anti-PD-1 Mimotope Vaccine Ready for Development
09/02/2018
Imugene hosts investigator meeting for gastric cancer clinical trial

Our Senior Management - profile and qualifications



Mr Paul Hopper

Executive Chairman
Paul Hopper has more than 20 years’ experience in international public company markets, with a focus on start-up and rapid growth companies where he has served as either Chairman, Non-Executive Director or CEO. His focus has been primarily in the life-sciences sector, steering around fourteen public companies in the US, Australia, and Asia.
Paul is an advisor at the Los Angeles-based Cappello Group where he is Head of the Life Sciences and Biotechnology Group responsible for mergers and acquisitions and capital raisings focusing on the biotechnology and life sciences sectors.
He is a Non-Executive Director of Prescient Therapeutics Ltd, Chairman of Viralytics Ltd and founder of Pathway Oncology.



Leslie Chong

Chief Executive Officer
Ms Chong most previously was a Senior Clinical Program Lead at Genentech, a member of the Roche family, in the head office in San Francisco. She has over 17 years of experience in leading clinical and department development in oncology. Most recently, she was the clinical operations program lead for the approved MEK inhibitor in cell-signalling targeted therapy, cobimetinib/Cotellic.
Prior to Genentech, Ms Chong was one of the clinical operation head at Exelixis, in development of 14 compounds and molecules. She has also been a member of the clinical operation department at GSK and PPD.
Leslie believes that early development and research innovation has the ability to bring transformative medicine to patients in need.



Mr Charles Walker

Non-Executive Director
Having spent around 20 years in the industry, Imugene NED Charles Walker is best known for his most recent role as CEO of Imugene Ltd, and also CEO, and earlier CFO, of Alchemia Limited. His three year tenure at Alchemia saw the launch and growth of sales of Alchemia’s first marketed product fondaparinux, the initiation of Phase III and Phase II clinical trials of Alchemia’s anti-cancer drug candidate HA-Irinotecan, the establishment of a partnership with Astra Zeneca AB and the establishment of a collaboration with Merck-Serono SA.

Prior to Alchemia, Charlie spent over a decade in corporate finance advising a variety of international technology companies and executing over 40 successful transactions including IPOs, M&A agreements and capital raisings.
Mr Walker possesses a deep understanding of life sciences financing and commercialisation, and his experience covers strategy, licensing, partnering, investor outreach and clinical trials. His education includes an MBA at Warwick Business School and a Pharmacology degree from the University of Bristol in the UK.


Dr Axel Hoos

Non-Executive Director
Dr. Axel Hoos is Senior Vice President and Therapeutic Area Head, Oncology R&D at GlaxoSmithKline Pharmaceuticals (GSK).  As leader of the Oncology TA he oversees both its discovery and development functions and builds the Oncology portfolio of GSK across several modalities including antibodies, small molecules, bispecific molecules and cell & gene therapies. The TA’s scientific focus is on Immuno-Oncology, Epigenetics and Cell Therapy.
Dr. Hoos also serves on the Scientific Advisory Board of the HIV Cure Center, a co-venture of GSK and the University of North Carolina at Chapel Hill.
Dr. Hoos further serves as Executive Chairman of the Board of Trustees of the Sabin Vaccine Institute (SVI), a Global Health organization, Co-Chairman of the Cancer Immunotherapy Consortium (CIC) and Scientific Advisory Board Member of the Cancer Research Institute (CRI). He further is a Scientific Advisory Group member at the Parker Institute for Cancer Immunotherapy (PICI), and Industry Co-Chair of the Partnership for Acceleration Cancer Therapies (PACT) of the U.S. Cancer Moonshot. His efforts in Medicines Development and Global Health focus on novel and transformational therapies for life-threatening diseases, scientific and procedural innovation, and broad collaboration across multiple constituents to solve complex health problems. Through his leadership a new paradigm for the development of cancer immunotherapies has been defined, which helped launch the field of Immuno-Oncology.
Previously, Dr. Hoos was the Global Medical Lead in Immunology/Oncology at Bristol-Myers Squibb (BMS) where he developed Yervoy (Ipilimumab), the first life-extending therapy in Immuno-Oncology. Before BMS, Dr. Hoos was Senior Director of Clinical Development at Agenus Bio (previously Antigenics), a biotech company.
Dr. Hoos holds an MD from Ruprecht-Karls-University and a PhD in molecular oncology from the German Cancer Research Center (DKFZ) both in Heidelberg, Germany. He trained in surgery at the Technical University in Munich, Germany and further in surgery, molecular pathology and tumor immunology at Memorial Sloan-Kettering Cancer Center in New York City. He is an alumnus of the Program for Leadership Development at Harvard Business School.



Professor Ursula Wiedermann

Chief Scientific Officer
Professor Wiedermann is Professor of Vaccinology and Head of the Institute of Specific Prophylaxis and Tropical Medicine of the Medical University Vienna. Currently she also has an appointment as Visiting Professor at the University in Göteborg, Sweden. She has more than 100 peer-reviewed publications and is frequently performing presentations at national and international conferences. Professor Wiedermann was the Principal Investigator for the preclinical development of HER-Vaxx and together with Prof. Zielinski´s Division the Phase I clinical trial of HER-Vaxx in metastatic breast cancer patients was performed. Furthermore she has led the design of the Phase II study for gastric cancer due to commence in 2015.
Professor Wiedermann had studied Medicine in Vienna, Austria. Between 1990-1995 she entered a PhD-program in Sweden at the Institute of Clinical Immunology at the University Gothenburg, focusing her research on mucosal immunity and vaccination. Back in Vienna she continued her research career at the University of Vienna concentrating on mucosal vaccination against allergic diseases. After her habilitation (venia docendi) in 1999 she founded the research group “Mucosal Immunity and Vaccination”. In 2001 she finished her medical training as specialist for “Immunology” and “Specific Prophylaxis and Tropical Hygiene”. At the Institute of Specific Prophylaxis and Tropical Medicine she enlarged her research areas to vaccine development against infectious diseases and tumours, and focused on clinical vaccine trials to study immune responsiveness and immune failures upon vaccination. In 2004 she became Head of the Institute of Specific Prophylaxis and Tropical Medicine of the Medical University Vienna and in 2006 she was assigned Professor for Vaccinology at the Medical University Vienna. She is a member of the Supreme Board of Health and the Chairman of the National Committee of Immunization Practice of the Austrian Ministry of Health. Since 2009 she is Speaker of the newly founded Centre for Geographic Medicine at the Medical University Vienna.


Dr Nick Ede

Chief Technology Officer
Dr Ede has a record of successfully evolving research concepts to commercial products and processes. He has over 25 years experience in drug discovery and international business development gained at Chiron Corporation - now Novartis (VP Chemistry), EqiTX Ltd (COO), Mimotopes Pty Ltd (CEO), Adistem Ltd (CEO) and Consegna Ltd (CTO). He has established joint ventures and partnerships with some of the leading pharmaceutical and biotechnology companies in the world, including a global peptide supply alliance with the world's 4th largest biotechnology company Genzyme Inc, Invitrogen Inc (exclusive peptide partnership), drug discovery partnerships with GSK, J&J and Novartis, and the Broad Institute (a joint venture of Harvard and MIT) and Infinity Pharmaceuticals (NASDAQ: INFI) where his combinatorial chemistry platform technology was installed and utilised for drug discovery projects. INFI chemists made over 260,000 structurally complex compounds on his platform, which helped raise >$60M in funding spread over three chemistry deals (Amgen, J&J, Novartis).  Additionally, screening these compounds initiated an oncology program, which was subsequently partnered (Novartis) and brought in an additional $30M.  He holds a PhD from Monash University and Grad. Cert. in Innovation from Melbourne Business School, and has published over 50 scientific papers and patents.