Ann: Phosphagenics Newsletter - March 2018, page-54

First 54 Last

Share
Profile

Follow
jevalent

5,270 Posts.

244

21/03/18

14:50

Post #: 31920796
Share

Originally posted by hottod ↑

The announcement seems to put blame for failure mainly on the company's inability to shrink the TPM-Oxymorphone patch to about the size of the existing Japanese fentanyl patch. The existing Durotep MT 16.8 milligram fentanyl patch measures about 6x7 cm. That is NOT a small patch.

However, this is a three day patch, so a one day version could be one third the size, or so it would seem.

That would make a one day fentanyl patch about credit card size....

Jev, a three day 16.8 mg fentanyl patch measures ~ 6 x 7 cm (42 sq cm) and, as you say, a one day patch could be one third the size of the three day patch (~ 14 sq cm?). Which you say would make a one day fentanyl patch about credit card size….

Now I don’t know about your credit cards, but mine measures 8.4 x 5.2 cm (43.6 sq cm).

By way of comparison, the oxymorphone patch tested in 2013 was 7.8 x 5.2 cm (40.5 sq cm) - so, slightly smaller than my credit card. That patch was reported to have delivered up to a level equivalent to 40 mg Oxymorphone ER.

I believe the existing one day fentanyl patch in Japan is Hisamitsu’s Fentos tape. It now ranges in dosage from .5mg. By way of example, the 2mg (one day fentanyl patch) is 3.17 x 3.17 cm (~10 sq cm); the 4mg patch is 4.48 x 4.48 cm (~20 sq cm). The 4mg Fentos Tape patch is equivalent to 80mg Oxycodone CR daily dose, which is equivalent to 40mg Oxymorphone ER daily dose.

http://www.rad-ar.or.jp/siori/english/kekka.cgi?n=33321

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062813/

Expand

I guess I don't have an instinctive feel for metric dimensions. You are correct in your assessment of the sizes (I ought to have taken the time to do actual conversions). Nevertheless, even if the one day TPM oxymorphone patch were to measure about 5x8 cm, it's difficult for me to see how that would be a deal killer. I think that other issues must have piled on.

POH Price at posting: 1.2¢ Sentiment: Hold Disclosure: Held
3 Upvote

0 Great analysis

Reply

Top Stories

The Altcoin Landscape (Part 1): Key alternative cryptocurrencies to watch

Bitcoin hits fresh record as instos pile into BTC ETFs – and Trump helps, too

Aussie inflation seemingly hit a 3 year low. So why's the ASX200 red?

Palladium's the newest geopolitical hot commodity. But ASX exposure is limited

Making money: How many microcaps should be in an investor's portfolio?

There are more pages in this discussion • 9 more messages in this thread...

First 54 Last

Add AVE (ASX) to my watchlist

(20min delay)
Last 0.2¢		Change 0.000(0.00%)		Mkt cap ! $6.338M

Open	High	Low	Value	Volume
0.2¢	0.2¢	0.2¢	$26	13K

Buyers (Bids)

No.	Vol.	Price($)
12	6848102	0.2¢

Sellers (Offers)

Price($)	Vol.	No.
0.3¢	41925822	29

View Market Depth

No.	Vol.	Price($)
12	6848102	0.002
26	68117741	0.001
0	0	0.000
0	0	0.000
0	0	0.000

Price($)	Vol.	No.
0.003	41925822	29
0.004	16347566	14
0.005	10075266	8
0.006	11115082	11
0.007	13229103	6

Last trade - 10.58am 01/11/2024 (20 minute delay)

AVE (ASX) Chart

Ann: Phosphagenics Newsletter - March 2018, page-54

The Altcoin Landscape (Part 1): Key alternative cryptocurrencies to watch

Bitcoin hits fresh record as instos pile into BTC ETFs – and Trump helps, too

Aussie inflation seemingly hit a 3 year low. So why's the ASX200 red?

Palladium's the newest geopolitical hot commodity. But ASX exposure is limited

Making money: How many microcaps should be in an investor's portfolio?

Featured News

Buyers (Bids)

Sellers (Offers)

Featured News

Ann: Phosphagenics Newsletter - March 2018, page-54

Top Stories

The Altcoin Landscape (Part 1): Key alternative cryptocurrencies to watch

Bitcoin hits fresh record as instos pile into BTC ETFs – and Trump helps, too

Aussie inflation seemingly hit a 3 year low. So why's the ASX200 red?

Palladium's the newest geopolitical hot commodity. But ASX exposure is limited

Making money: How many microcaps should be in an investor's portfolio?

Featured News

Buyers (Bids)

Sellers (Offers)

Featured News