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Ann: MPS RECEIVES CRITICAL APPROVALS AND FEEDBACK FROM AGENCIES, page-12

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  1. 1,151 Posts.
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    Here you go. Looks like a great resource for MPS
    https://www.mpssociety.org.au/about-the-mps-and-related-diseases/mps-i/


    HOW COMMON IS MPS I?
    It has been estimated that about 1 in 80,000 births are affected by MPS I. Hurler syndrome represents about 1 in 88,000 births; Scheie syndrome about 1 in 500,000 births; and Hurler-Scheie syndrome is about 1 in 115,000 births.

    The incidence of all MPS disorders combined [of which 11 are currently recognised] is estimated to be 1 in 25,000 births.

    The MPS group of disorders are part of a larger family of about 50 inherited disorders called lysosomal storage disorders, so named because storage of materials that are unable to be properly degraded (mucopolysaccharides in the case of the MPS disorders) occurs in the lysosome. It is estimated that lysosomal storage disorders occur in about 1 in every 5,000 to 7,000 births.
    Last edited by Hrdwk: 11/08/20
 
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