IBX 4.35% 4.8¢ imagion biosystems limited

Interesting, page-1905

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    The link os that the study states IBX’s SPIONs perform better. Hyperfine might need to partner with IBX to market their “printer”


    The HS-SPIONs have measured magnetizations at ULF over 3000 times larger than conventional Gd-DTPA CAs (see characterization data of MRI CAs at 6.5 mT in Table 1). As the SPION magnetic moments fluctuate, they couple to nearby 1H nuclei (see Fig. 1C), causing a shortening of spin relaxation times. We observe that HS-SPIONs have ULF spin-lattice (r1) and spin-spin (r2) relaxivity values in excess of 300 mM −1 s−1, nearly two orders of magnitude larger than observed for the Gd-DTPA. Relaxivity values for the HS-SPIONs are approximately 10 times that observed for ferumoxytol SPIONs, predominantly due to the higher magnetization reached in the larger iron oxide cores of the HS-SPIONs (22, 26).

 
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