DXB 5.32% 49.5¢ dimerix limited

Ann: Dimerix Plans for Next Study in Diabetic Kidney Disease, page-19

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  1. 6,434 Posts.
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    https://hotcopper.com.au/data/attachments/2847/2847897-b343b38db32d0ae30e0d2a2813f80fc4.jpg
    The numbers are good. If you go & look at some post hoc analysis of Cana, there was a broad range in reduction of UACR dependent on starting baseline.

    The subgroup in DKD DMX-200 trial 500mg/L or greater achieved a 37-38% reduction in UACR. Compare that to the above of 31% at week 26 with a cohort of >300mg/L. We know from the CREDENCE trial that UACR & eGFR decline & then plateau at 26 weeks.

    https://hotcopper.com.au/data/attachments/2847/2847930-d2cf942e69f0ed0c0c73a0d3187f1290.jpg

    I’m sure there is loads to discuss here, catch up later
 
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