Ann: Pre-Submission package lodged with the US FDA, page-25

Where does it say RAP were after PPA and NPA of 80-85% and not 75-80%? There was a recent study done by MGH which show doctor diagnosis of respiratory consultation are less than 70% accurate hence why do you think 33% of the time even the doctor in the best hospital had trouble reaching a clinical diagnosis in the clinical trial.

"In the case of 429 patients (33% of the total) agreement on the clinical diagnosis was not reached between two adjudicators and a third adjudicator was required to reach a majority consensus, which highlights the scale of the challenge faced when diagnosing respiratory illnesses. "