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Augmenting HER2 Inhibition by Targeting PI3K – Lessons From Metastatic Brain Cancer

  1. dking99
    375 Posts.
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    12/02/21
    22:05
    Post #: 50948598
    24 Jun 2021 10AM
    Augmenting HER2 Inhibition by Targeting PI3K – Lessons From Metastatic Brain Cancer

    PI3K is part of the signaling cascade for HER2 and therefore drugs modulating both targets are potentially synergistic•

    PI3K inhibition has been explored as a means to overcome resistance to HER2-directed therapies• Paxalisib, a brain-penetrant PI3K inhibitor, is under investigation for HER2+ breast cancer brain metastases

    https://her2-targeted-therapies.com/whats-on/agenda/day-two/

    KZA Price at posting: $1.26 Sentiment: Buy Disclosure: Held
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