Ann: Booking.com for Business Partnership, page-44

Substantial Shareholders as of 29 03 2021

	Shareholders	Share Holding​	Shares Held​
1	Geoffrey Hosking	23,751,925​	25.61%​
2	Robert Shaw	12,943,426​	13.96%​
3	Darrin Grafton	12,232,868​	13.19%​
4	Harbour Asset Management Limited	8,223,424​	8.87%​
5	Milford Asset Management Limited	5,773,273​	6.22%​

Booking, or anyone else, is unlikely to consider even a partial takeover unless they have a strategy to create dissent among the top three holders.
So the share price probably includes no takeover premium and won't for the foreseeable future.