Also replying in case it may benefit others. Your opinion or questions are of little concern to me, as you lack sincerity + credibility.
- The wheeze measurement technology using PulmoTrack has been published in multiple journals over the past 20 years.
- The first version was designed for hospital - it was the first FDA approved electronic wheeze monitor called Pulmotrack (1998)
- It was based on real time monitoring of wheeze and cough
- Pulmotrack consists of 2 acoustic sensors to identify breath sounds and wheeze at the trachea and chest, and an ambient microphone
- The inventor's work was published in his book
N. Gavirely, Breath Sound Methodology, CRC Press, 1995
- Respiri has previously discussed its focus on a wheeze severity index, and with ongoing work towards inclusion in Respiratory journals this is not something that can be discussed until completion of the process.
- Wheezo uses the state-of-the-art micro-electromechanical system (MEMS) microphone to pick up the breath sounds
- Wheezo detects and measures wheeze, similar to PulmoTrack, over 30 seconds of recording on the trachea
- The Wheeze detection algorithm has been improved over time since PulmoTrack.
- As part of preparation for CE certification in 2019, and then FDA clinical evaluation reports were prepared to provide evidence that the device achieves its intended purpose without subjecting patients to additional risk. The report for CE was reviewed by Prof. Frank Thien.
- Various organisations such as Asthma Australia, and GINA have guidelines and recommendations around the importance of listening in for wheeze and assessing severity. This is obviously difficult to do out of a clinic setting, without a device that can make these objective assessments/measurements. Especially as not all wheeze is audible. And an approach utilising a smartphone microphone also has its limitations. Hence RSH/Wheezo enable patients to follow existing guidelines from the most credible clinical organisations with greater ease/accuracy.
Researchers have used PulmoTrack in publications to study the wheeze in children as shown below
• P. Prodhan, R. S Dela Rosa, M. Shubina, K. E. Haver, B. D. Matthews, S. Buck, R. M. Kacmarek, and N. N. Noviski, "Wheeze Detection in the Pediatric Intensive Care Unit: Comparison Among Physician, Nurses, Respiratory Therapists, and a Computerized Respiratory Sound Monitor", Respiratory Care, Vol .53, No. 10, pp. 1304-1309, 2008.
• M. L. Levy, S. Godfrey S., C. S. Irving, A. Sheikh, W. Hanekom, A. Bush, and P. Lachman, “Wheeze detection: recordings vs. assessment of physician and parent,” J Asthma. Vol. 41, No. 8, pp. 845-53, 2004.
• L. C. Puder, S. Wilitzki, C. Bührer, H. S. Fischer, G. Schmalisch, “Computerized wheeze detection in young infants: comparison of signals from tracheal and chest wall sensors,” Physiol Meas., Vol. 37, No. 12, pp. 2170-2180, 2016.
• H. S. Fischer, L. C. Puder, S. Wilitzki, J. Usemann, C. Bührer, S. Godfrey, G. Schmalisch, “Relationship between computerized wheeze detection and lung function parameters in young infants,” Pediatr Pulmonol., Vol. 51, No. 4, pp. 402-410, 2016.
• L. C. Puder, H. S. Fischer, S. Wilitzki, J. Usemann, S. Godfrey, G. Schmalisch, “Validation of computerized wheeze detection in young infants during the first months of life,” BMC Pediatr., Vol. 9, 2014.
• A. L. Boner, G. L. Piacentini, D. G. Peroni, C. S. Irving, D. Goldstein, N. Gavriely, S. Godfrey, “Children with nocturnal asthma wheeze intermittently during sleep,” J Asthma. Vol. 47, No. 3, pp. 290-294, 2010.
• B. Raphael, N. Elias, S. Shoval, N. Tov, G. Talmon, S. Godfrey, and L. Bentur, “Computerized acoustic assessment of treatment efficacy of nebulized epinephrine and albuterol in RSV bronchiolitis,” BMC Pediatr., 2007.
• L. Bentur, R. Beck, M. Shinawi, T. Naveh, N. Gavriely, “Wheeze monitoring in children for assessment of nocturnal asthma and response to therapy,” Eur Respir J., Vol. 21, No. 4, pp. 621-626, 2003.
• J. B. Eising, C. S. Uiterwaal, C. K. van der Ent,“Nocturnal wheeze measurement in preschool children,” Pediatr Pulmonol., Vol. 49, No. 3, pp. 257-262, 2014.
• N. Gavriely, O. Lakser, K. Maklezow, S. Godfrey, “Ambient And Chest Confined Wheezing And Extreme FEV1 Drop Post Exercise In 17 Year Old Asthmatic With Exercise-Induced Shortness Of Breath (SOB): A Case Report,” American Journal of Respiratory and Critical Care Medicine, Vol 183, A4556, 2011.
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