@MisterMister
enter PARA-006
938 subjects
https://clinicaltrials.gov/ct2/show/record/NCT04814719
- Change in subchondral Bone Marrow Lesion (BML) area and volume on Magnetic Resonance Imaging (MRI) from baseline of the parent study at Week 28 and 80 [ Time Frame: Baseline (parent study), Week 28 and 80 ]
MRIs will be reviewed by an independent trained reader blinded to participant characteristics, study information and timing of MRI scans. All measurement will be done in duplicate- Change in joint synovitis/effusion volume on MRI from baseline of the parent study at Week 28 and 80 [ Time Frame: Baseline (parent study), Week 28 and 80 ]
MRIs will be reviewed by an independent trained reader blinded to participant characteristics, study information and timing of MRI scans. All measurement will be done in duplicate- Change in cartilage volume on MRI from baseline of the parent study at Week 28 and 80 [ Time Frame: Baseline (parent study), Week 28 and 80 ]
MRIs will be reviewed by an independent trained reader blinded to participant characteristics, study information and timing of MRI scans. All measurement will be done in duplicate- Change in bone shape on MRI from baseline of the parent study at Week 28 and 80 [ Time Frame: Baseline (parent study), Week 28 and 80 ]
MRIs will be reviewed by an independent trained reader blinded to participant characteristics, study information and timing of MRI scans. All measurement will be done in duplicate- Change in joint space width on X-ray from baseline of the parent study at Week 28 and 80 [ Time Frame: Baseline (parent study), Week 28 and 80 ]
X-Rays will be reviewed by an independent trained reader blinded to participant characteristics, study information and timing of MRI scans. All measurement will be done in duplicate- Change in joint space width on MRI from baseline of the parent study at Week 28 and 80 [ Time Frame: Baseline (parent study), Week 28 and 80 ]
MRIs will be reviewed by an independent trained reader blinded to participant characteristics, study information and timing of MRI scans. All measurement will be done in duplicate
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