Good in that it seems to be efficacious, at least a bit more than methotrexate and appears to have some DMARD effects in some patients.
Bad in that it does cause side effects, some are serious AND the FDA has slapped a boxed warning on it. It can tend to weaken some patient's immune systems. Some 0.2% in clinical studies developed TB. (Known to increase chances of TB when immune systems are compromised for example). 0.2% may not sound like much but multiply it out by the numbers that may one day use this drug.
Just my views
Ann: PARADIGM RECEIVES FEEDBACK FROM US FDA ON IND SUBMISSION, page-145
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Last
24.5¢ |
Change
0.015(6.52%) |
Mkt cap ! $85.73M | |||
| Open | High | Low | Value | Volume |
| 23.5¢ | 24.5¢ | 21.5¢ | $328.0K | 1.416M |
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| No. | Vol. | Price($) |
|---|---|---|
| 1 | 100000 | 23.5¢ |
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| Price($) | Vol. | No. |
|---|---|---|
| 24.5¢ | 19775 | 1 |
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| Last trade - 16.10pm 19/11/2024 (20 minute delay) ? |
| PAR (ASX) Chart |