Agree that deal time is during P3 (and we do have MPS as well which is more advanced and still a sizable prize - the theory about BioMarin being interested seems pretty strong).
I think its the whole point about 008 - early data on the structural biomarker endpoints, which indicates DMOAD, which makes the asset more attractive, which increases deal value, facilitates negotiations during P3, etc.. Its the main reason we are doing 008 early (and outside the P3), to get this data in house to leverage discussions during the P3
Sorry to harp on about DMOAD, but its pretty mind blowing. Since that link I posted earlier was pretty dodgy I'll try again........ FDA STRUCTURAL ENDPOINTS FOR OA
Further to this paper by FDA in 2018, the OARSI wrote this piece which really spells it out the route to DMOAD completely, and seems to mesh with our trial structure including a biomarker as a surrogate endpoint,.....RESPONSE TO FDA ON STRUCTURAL ENDPOINTS
Something for @Mozzarc to get his teeth stuck into.
- Forums
- ASX - By Stock
- PAR
- Ann: PARADIGM RECEIVES FEEDBACK FROM US FDA ON IND SUBMISSION
Ann: PARADIGM RECEIVES FEEDBACK FROM US FDA ON IND SUBMISSION, page-168
-
- There are more pages in this discussion • 127 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
NEWS
Exceptional lithium assays uncovered at Falcon Lake – expanding mineralisation, big potential ahead
NEWS
Biotech innovator secures $5.5M R&D tax incentive refund – major boost for cutting-edge programs
Add PAR (ASX) to my watchlist
|
|||||
Last
25.5¢ |
Change
0.010(4.08%) |
Mkt cap ! $89.31M |
Open | High | Low | Value | Volume |
25.0¢ | 26.5¢ | 25.0¢ | $199.1K | 773.8K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
3 | 114831 | 25.5¢ |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
26.0¢ | 29273 | 2 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
2 | 109831 | 0.255 |
4 | 93086 | 0.250 |
3 | 43355 | 0.240 |
2 | 50000 | 0.235 |
8 | 113649 | 0.230 |
Price($) | Vol. | No. |
---|---|---|
0.260 | 29273 | 2 |
0.265 | 64378 | 2 |
0.270 | 31581 | 3 |
0.275 | 23636 | 3 |
0.280 | 89933 | 5 |
Last trade - 16.10pm 12/09/2024 (20 minute delay) ? |
Featured News
PAR (ASX) Chart |