The whole idea of 008 is to take out the relevance of any placebo effect in any case as the Bio Marker results and various scans can’t and won’t lie.
For me the benefit of the dog trial is less for the FDA (although it all helps) and more for expediting partnering discussions by getting hold of some compelling bio marker results a lot earlier and adding massive value to the discussions.
On 008 I don’t think the company would have any results of participants to date. Anyway, the company knows exactly what it does and how it works. This gives the confidence to make the changes they make.
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