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19:53
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Originally posted by turbo:
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I've addressed the issue of the cell surface complex in a post elsewhere here. Basically, it will be important to identify the CLTX ligand to add granularity to which other cancers this therapeutic will be most effective against and potentially patient stratification but, since MMP-2 is associated with the complex and is acting just fine as a proxy, it is not a pressing issue. Technically, this is neither difficult or expensive to solve, it just requires time for the experiments to be done. Not a biggie though.
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CHM used the words, “….. an unresolved question of increasing importance”.
(20min delay)