Ann: Sponsored Research Agreement with University of Pennsylvania, page-7

U Penn are the inventor of Car-T and the grandaddy of Car-T and Cell therapy. Penn innovations in Car-T have already generated development/takeovers of $20 billion+. This also further establishes a deeper relationship for other licensing opportunities Penn may have simmering away in the back ground.

CHM will want to get this to clinic asap and are on schedule. It’s been in development for 10 years at Penn. CDH 17 CAR T therapy is now in 3rd Generation, with 2nd gen having some success in tumor eradication (red line below), but the 3rd gen CAR T the university of Penn has developed far surpasses anything we've seen in terms of eradication of tumor cells i.e. complete eradication and no relapse (green line below). With Dr Hua the inventor and his team on this for the next 3 years it will be in professional hands. Extremely promising.

Progressing well with a diverse portfolio of solid tumour annihilators!