MSB All-time low Party Thread, page-270

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    in 309 patients treated in japan since 2016.
    the average age was 49
    the average days from gvhd onset to msc therapy was 27 days
    24% had liver involvement
    30% had 2 therapies prior to msc

    improved response and survival rate was associated with patients that were
    under 18
    treated within 14 days
    had non liver involvement
    had less than 3 or 4 prior therapies.

    other therapies include ruxolinitnib, inolimomab, anithymocyte globulin. across the entire study group cells remain viable treatment option.

    but when used on the right patients at the right time it is even better. the one size fits all approach being used in japan provides real world evidence for a more targeted application.

    yet the market penetration remains high. see the chart for evaluation of % market share for drugs when others are first available.
    https://hotcopper.com.au/data/attachments/4479/4479553-e4875dd05ed8848c757d2af4aa90181b.jpg
    https://hotcopper.com.au/data/attachments/4479/4479556-fd39d12a42d906a595bae2735cff09bd.jpg
 
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