Hi Phaedrus, I like your post.
You and dachopper both look closely at MSB announcements and almost make transcripts - I like that about you guys because then people willing to look can check things for themselves and then we can have discussions based on agreed facts.
Your post includes, with two time stamps, two quotes from Dr Eric Rose. Those quotes and timestamps are accurate in my opinion but Dr Eric Rose said some things in between them that are also relevant I think. And they might help us work out where we disagree how the facts of what Dr Eric Rose has said influences our current interpretations.
Here is a cut and paste of a part transcript I made around the 10th of June, I think after seeing Dachopper post, I can't recall if I saw yours, I think I didn't because when you refer to it, I really like it.
Number in brackets roughly line up with time stamps - the blue bits are the parts you've already quoted. But I think there is some other relevant material in between - I'll yellow that.
[Dr Rose] Um, I thinkultimately I believe approval will be based on a totality (42.04) ofthe evidence. Ah, and we, as shown at the panel, the clinical dataare quite convincing (42.15), um, thepotency assay that we originally proposed (42.22), ah, hadproblems. And we’ve reverted to a new potency assay(42.32), um, that speaks to the mechanism of action of the cells(42.39) as an anti-T cell ahah entity (42.45). And we’vealso been able to demonstrate a clinical correlation between thepotency assay and outcomes. (42.56) ah, when measured by, ah, disease severity measured by stage or by MAP score (43.06) ah, andlastly (43.11) ah, we’ve overcome some supply chain issues thathave been required to (43.17) finish the potency assay for theinventory (43.21) that we’ve already built. Ah for the commercialproducts. (43.25) Ah, that we’rein the process now (43.31) ofvalidating. And those three things: clinical effectiveness;(43.40), um, potency assay (43.45) and reagents to actually do the potency assay on our (43.53) existinginventory ah, we think willcarry the day. (43.58) . ah, and as a totality of the evidence,particularly for patient group (44.09) that’s this sick and has this high a mortality (44.13) and this high a morbidity, we feel ahconfident in the products. (44.19) .
I want to give people some time to check and see that that transcript is pretty accurate - that I'm not trying to kid or mislead anyone. And I want to have a discussion where others can point out if I'm myself mistaken.
I hope to come back to engage further with the comments in your post later.
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