Ann: Q&A on NTI164 Breakthrough Clinical Trial Results in ASD, page-2

Love the new news that is often hidden in the NTI updates...

I dont recall this being noted inthe Webinar...

Qn - Do the results to date encourage Neurotech to undertake studies for other neurological
conditions?
Ans - " .......We are planning for the commencement of a Phase I/II trials in Cerebral
Palsy and Long Covid later this year.

Why is this relevant -

From the Yale School of medicine:

"Since the pandemic’s onset, it has become clear to neurologists that the pervasive disease can impact even our most precious organ—the brain. The neurologic and psychiatric complications of COVID-19 are incredibly diverse and sometimes persist long after patients recover from their initial infections. Studying the mechanisms behind how these complications arise is urgently needed for helping those struggling with lingering symptoms"

Even with mild cases, COVID-19 can cause confusion, delirium, sleepiness, poor cognitive function, intense headaches, and uncomfortable skin sensations. In more severe cases, patients have suffered complications as serious as strokes.While researchers initially focused on complications during the acute stage of the disease, as the pandemic progressed they soon realized many of these complications could be long lasting.“There are many, many reports now of people having persistent symptoms for months. That’s being termed ‘long COVID,’” says Spudich. “Often, they’ve had complete resolution of their fevers and breathing problems, but they continue to have problems with thinking, concentration, memory, or difficulty with strange sensations and headaches.”

“In our paper, we accumulated evidence that has been systematically investigated and summarized how the brain is affected during acute COVID-19,” says Spudich. “We found that most of the research points to immune-system mediated injury rather than the virus actually entering the brain and killing cells there. ”Researchers can look for the presence of pathogens in the nervous system through studying cerebrospinal fluid (CSF)—the liquid around our brain and spine. Of the many studies that have been conducted worldwide, very few have detected SARS-CoV-2 remnants in the CSF. Furthermore, autopsy studies—which can sometimes detect viral fragments in the brain—have also failed to find remaining particles .However, even in the absence of a replicating virus, COVID-19 may still contribute to immunologic changes. Specifically, studies have pointed to an elevation in markers of immune activation and inflammation in the CSF and brain that may underlie symptoms. For example, immune cells release certain proteins to fight infection, but those can also have off-target effects that interfere with neurological function.“ We believe that in some people who get COVID and suffer neurological symptoms, the immune system is causing changes in the nervous system that end up making them symptomatic,”


So why does NTI target long covid.? There seems to be a link between they symptoms and Inflammation in the Brain... What do we have a high degree of cinfidence that NTI164 is good at doing... Reducing inflamation in the brain.... BINGO...

SP is slow to move as almost everyone is set, and still concerned re a cap raise... So it is slow going until we get a deal IMHO.