And then a 2021 meta-analysis of 8 studies showing that the cartilage increases but has no benefit whatsoever.
"The data from the included studies provide strong evidence to determine the effect of intra-articular sprifermin on joint structure in individuals with KOA and show no specific adverse effects. Nevertheless, intra-articular sprifermin did not likely have any positive effect on symptom alleviation."
I'm sure patients will be lining up....
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