This is from last year's annual report 14th Oct 2021 - less than 12 months ago!!!:
"Enrolment and patient treatment commenced in
MEND respiratory failure trial
Following commencement in August 2020, Cynata
received ethics committee approval in March 2021
to expand the recruitment criteria of the MEND
(MEseNchymal coviD-19) clinical trial to include
patients admitted to an ICU with respiratory failure of
any cause. The expansion is expected to accelerate
recruitment into the trial by increasing the pool of
eligible patients with COVID-19 no longer a limiting
requirement for eligibility.
Cynata achieved a significant milestone by treating
the first patient in the trial in May 2021. The openlabel randomised controlled clinical trial design aims
to investigate the safety and early efficacy of Cymerus
MSCs in 24 adult patients with respiratory failure.
The trial will involve 12 critically infected patients
randomised to receive Cymerus MSC infusions, in
addition to standard of care, and 12 patients who will
be randomised to the control group and will receive
current standard of care only. Given the seasonal
nature of the incidence of respiratory distress and the
highly uncertain situation around COVID-19 outbreaks
in Australia at present, Cynata is currently unable to
provide firm guidance on when trial results might be
expected. However, it is currently estimated that the
trial will complete late in calendar 2021. The trial is
fully funded by Cynata’s existing cash reserves.
Cynata has identified acute respiratory distress
syndrome (ARDS), sepsis, and cytokine release
syndrome (CRS) as targets relevant to the outcome
of this trial, as they present significant unmet medical
needs, and are manifestations of the excessive
inflammatory responses typically seen in acutely
Then the trial was expanded further to include more hospitals. Then it was abandoned.
You couldn't get 24 patients after all that???
24???!!!!
There is more than 24 in the ICU's across Australia for Covid 19 right now!!!
Why don't the shareholders want to know more????
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- Ann: Cynata Expands trial in COVID-19 & Respiratory Failure
Ann: Cynata Expands trial in COVID-19 & Respiratory Failure, page-174
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