CYP cynata therapeutics limited

Ann: FDA Clears Cynata IND for Phase 2 Trial in GvHD, page-64

  1. 1,315 Posts.
    lightbulb Created with Sketch. 3973
    https://hotcopper.com.au/data/attachments/4959/4959856-bd67dde50ae80d50b326e8e5278f8480.jpg
    https://hotcopper.com.au/data/attachments/4959/4959864-03c7ceb777458f6b90f41256aaabb277.jpg
    https://www.sciencedirect.com/science/article/pii/S1083879119304495#:~:text=Steroid%2Drefractory%20aGVHD%20was%20defined,after%20completion%20of%20steroid%20taper.

    https://hotcopper.com.au/data/attachments/4959/4959873-b254ed3dd8f39218b2ebec694b4f0c67.jpg
    https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2141.2012.09129.x

    https://hotcopper.com.au/data/attachments/4959/4959882-5abd04d5cca6a9c14717da7cbfec0b03.jpg
    https://journals.sagepub.com/doi/full/10.1177/2040620713489842


    Adding "All enrolled subjects in this trial must receive corticosteroids at a minimum dose of oral prednisone 2 mg/kg/day (or methylprednisolone 1.6 mg/kg/day IV) as therapy for aGvHD for at least for 72 hours post enrollment" is in my opinion CYP's approach to standardise the P2 trial and is in line with current first-line therapies for newly diagnosed patients with high-risk aGvHD.


    The above is also in line with other clinical trials (past and present) for newly diagnosed patients with high-risk aGvHD:

    https://hotcopper.com.au/data/attachments/4959/4959948-d394c8420b330dcc8c22592659b637ee.jpg
    https://www.sciencedirect.com/science/article/pii/S1083879109001530

    https://hotcopper.com.au/data/attachments/4959/4959951-2cab28155cca5526a0ffea946a9a24db.jpg
    https://clinicaltrials.gov/ct2/show/NCT04397367

    https://hotcopper.com.au/data/attachments/4959/4959952-014eb6b72493bee55b1c921ba5804cbd.jpg
    https://clinicaltrials.gov/ct2/show/NCT01002742


    The desperation displayed by the lack of any meaningful content, cock-eyed-"IMHO"-conclusions - in attempts to discredit a stock that is currently valued at a MC of just over A$42 million - by investors of MSB is well received by the way. Especially the frequency of these poor attempts show how much CYP is on your minds, despite our current SP of A$0.29. I take that as a compliment and for that I thank you.
 
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