From the article:
"Whilst significant reductions in pain NRS and KOOS subscales were observed in this study, these were of similar magnitude to changes seen over similar periods in the placebo arm of recent placebo-controlled knee OA pharmacological RCTs. Moreover, it is not a randomised clinical trial (RCT) and there is no control group, the placebo response could be playing an important role in this open-label study."
In short, the oral formulation doesn't work.
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