Joe, in respond to your earlier question, the short answer is 'no' (I am not 100% confident with my literature coverage though, as oncology is not my research field). With the saying of no other lines combo is working better than efti/keytruda, I need to put the condition on top that we have to comparing similar class of treatment type, i.e., IO-IO combo or IO-targeted therapy combo for the least. With any chemo-IO combo, even some of them get higher ORR, the quality of responding would be no where comparable.
A short sum up is that efti/keytruda combo in the field of chemo free treatment, is surely a few of the best, if not THE best.
While the science again summits over many other big companies, I am as much upset about the price as all here.
I do observe that the trading pattern for the last few days would be worth noting.
The daily short sell since last week showing 'shorting' activities increased. If you look at it as the percentage of the whole company, even on last Fri, the short sell volume was only 0.1% or 885k shares, not much weighting over the whole. However, on Fri, the total traded volume was only 1.4mil shares, meaning over 60% of the trade volume was short sell. Then the previous few days were all like that, over 50% of daily traded volume was short sell.
With that kind of shorting mounted on daily basis, the share price definitely can not go 'up'.
To me, this is not the typical Hedge fund play, of which they try profiting from the large price movement and large volume. As a matter of fact, the value equivalant of daily trades these days are struggling to pass $A400K. So any of these short/long playing is not going to generate much profit even they always get it done perfectly.
(percentage of daily short can be checked here
https://adgss.lvlworld.com/; the actual daily short sell number can be checked at
https://www.asx.com.au/data/shortsell.txt; open short positions with 4 days lag can be checked at
https://www.shortman.com.au/; these are all relevant.)
Then the only remaining sensible explaination is that someone just does NOT want it to go 'up'.
I do not think they press the price because they try to accumulate now. As there is no accumulation at all, no much volume.
As for why is that, I am sure you guys have much better theroy to fit the observation.
(20min delay)