The interim DIPG combo data is imminent if the schedule of milestones is somewhat correct and there are a few conferences in the coming 4 months, most notably SNO in June where the DIPG data is well placed.
https://www.soc-neuro-onc.org/WEB/WEB/Events.aspx
If the data is relatively in line with the experience from case reports then I translate previous JG's comments on the willingness of regulatory bodies to look at the evidence in such underserved, high-need areas as "We will align our regulatory strategy with Chimerix and prepare the documents for a (conditional) regulatory approval".
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