Ann: Excellent initial Overall Survival Benefit in 1st line NSCLC, page-2

More great news for cancer patients and for us stunned mullets invested here.

“...This immuno-oncology (IO) investigational combination, without the use of chemotherapy, led to excellent initial survival results in the overall intent-to-treat (ITT) 1L NSCLC patient population (N=114), regardless of PD-L1 expression status. Importantly, an initial median OS of 25 months has been attained in those 1L NSCLC patients (N=58) who have a PD-L1 Tumor Proportion Score (TPS) of >1%, a key area of focus for efti’s future clinical development and for which Fast Track designation was granted in October 2022.”

”...Collectively, the breadth of efficacy and safety data emerging from the large number of 1L NSCLC patients in the Phase II TACTI-002 trial offers compelling evidence of efti’s substantial impact in safely stimulating the patients’ immune response to fight cancer. These initial OS results are supported by a strong interim median Duration of Response of 21.6 months in the ITT population (N=114), including over one-third of patients with negative PD-L1 expression (N=32), and the high 48.3% response rate achieved with efti in combination with pembrolizumab in 1L NSCLC patients with a PD-L1 TPS of >1% (N=58), as reported in a late-breaking oral abstract presentation at the Society for Immunotherapy of Cancer (SITC) Meeting in 2022.”