A lot of money has been wasted on pursuing so many indications with failed trials. It would have been better to do a a proper phase 2 trial on aGVHD, demonstrate efficacy and then a proper phase 3 RCT trial that would have convinced the FDA. Once that was established with revenues choose another indication. The scatter gun failed phase 2 followed by failed phase 3 approach justified by "lots of biotechs lose a billion dollars get used to it" seems a bit cavalier.
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