In todays NYT, a very interesting article highlighting the sort of deals/partnerships that are possible with big pharma from the results of small, early stage trials, that show 'impressive' results.
In this case, in a trial of only 10 patients, who had severe heart desease, where previous treatments had failed to reduce their cholesterol , they were treated with an experimental cholesterol-lowering treatment using gene editing. Researchers reported that 'the treatment appeared to reduce cholesterol levels markedly in patients and that it appeared to be safe'.
Eli Lilly have paid $60 million to to collaborate with Verve Therapeutics and opted to acquire additional rights to Verve’s programs for an additional $250 million. If the editing continues to look promising, Eli Lilly expects to help with larger studies.
https://1ft.io/proxy?q=https%3A%2F%2Fwww.nytimes.com%2F2023%2F11%2F12%2Fhealth%2Fcholesterol-gene-editing-study.html
AML partnership anyone ??
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