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PTX Media related, page-1570

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    Tiger is quite right. Whilst the efficacy resutls are exceptional, the safety profile is not and, in fact, I don't know how the author of the article could possibly refer to the drug as safe given the details:-

    "The drug was found to be safe, with manageable side effects, including cytokine-release syndrome in four patients and immune-cell-related neurotoxicity syndrome in three patients. One patient experienced grade 3 sepsis that resolved; the same patient later developed fatal neutropenic septic shock outside the dose-limiting toxicity time frame."

    The specific type of NHL being trialed is B-cell non-Hodgkin Lymphoma. From the following list of main subtypes listed on the Lymphoma Aust website, you can see where PTCL and CTCL sit;-


    https://hotcopper.com.au/data/attachments/5842/5842470-0c66b45f41ac81bfcdd59638d50c87aa.jpg



    What's interesting is the following slide from our PTX-100 Spotlight Presentation that shows the indications of interest for PTX-100:-

    https://hotcopper.com.au/data/attachments/5842/5842477-baab73d296e09e2203c9aba81f0fd07e.jpg

 
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