"Not only would way more people happily submit to the test but the savings to the health industry of having to avoid a boatload of unnecessary colonoscopies"
Actually, this is incorrect "unnecessary colonoscopies" is driven by the false positive rate that is a function of specificity of the assay. FIT has higher specificity than ColoSTAT (96% versus 91% hence FP rates of 4% and 9% respectively).
In other words, for every 50K people screened (assuming a CRC prevalence of 0.49%) then FIT will produce ~1,800 FP / unnecessary colonoscopies but ColoSTAT will be ~4,500 unnecessary colonoscopies.
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