I think that is what makes the biotech sector a very interesting place to invest and the learning about these method of actions discovered either through new drug development or repurposing of existing drug compounds and drug combinations is of interest to me.
To your point, it is a bit mind blowing how this happens but drug repurposing seems to be fairly common and can be a quicker way of drug development.
PAA discovered that Monepental also inhibited the mTOR pathway which induces autophagy which means it could be potentially used to treat things like cancer and neurodegeneration which is totally different to the original target method of the drug. Similarly another company PAR discovered that Pentosan polysulfate sodium which is used orally to treat bladder conditions could also be used as an injection to treat osteoarthritis due to its anti-inflammatory properties but it also appears through MRI scans that the drug helps regenerate the worn cartilage.
For disclosure I have investments in both PAA and PAR.
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