great post @reon1 adding to this we know Monepantel is a potent mTor inhibitor that has a great safety profile and crosses the BBB. We should be anticipating pipeline update / preclinicals for other neurodegenerative dieseases this month, potentially alzheimers.
source: https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1366061/full#:~:text=Research%20shows%20mTOR%20activation%20as,are%20reversed%20upon%20mTOR%20inhibition.
Chatgpt
Looks like Monepantel is in prime position as a neurodegenerative treatment.
Ann: OLE Study update reveals impressive Survival Data, page-202
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