AZER-CEL OFF-THE-SHELF (ALLOGENEIC) CAR T
Why has Imugene management prioritised Azer-cel in the last 4 months presentations?
Are they quietly confident of the data to date, as they say, first-to-market potential,
currently in Phase 1b trial potential for registrational Phase 2/3 trial for FDA approval.
Azer-cel could be the first approved allogeneic CAR T therapy for patients with DLBCL who
failed autologous CAR T.
In addition to the above study, pre-clinical studies at City of Hope have started, combining Azer-cel with Imugene's onCARlytics (CF33-CD19), generating FDA data.
Deep dive into Allogeneic CAR T - recent article Allogeneic CAR-T Therapy Technologies: Has the Promise Been Met?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10814647/
Regards.
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