Hi @strangelogic,
' OA is a big problem with significant comorbid diseases so that may have some influence. (Anxiety, Depression, Fibromyalgia, Diabetes mellitis, Hypertension, chronic Kidney disease, NSAID complications, and obesity)'
Strong argument, and let's not forget the harm that can be done by opioids - iPPS would not in itself save lives. But indirectly, by replacing a drug that has the potential to do great harm, it will save lives.
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